Version 5.4
Homo sapiens Gene: KPTN
Summary
InnateDB Gene IDBG-59574.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KPTN
Gene Name kaptin (actin binding protein)
Synonyms 2E4; MRT41
Species Homo sapiens
Ensembl Gene ENSG00000118162
Encoded Proteins
IDBP-59576
kaptin (actin binding protein)
IDBP-761026
IDBP-766010
IDBP-761963
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a filamentous-actin-associated protein, which is involved in actin dynamics and plays an important role in neuromorphogenesis. Mutations in this gene result in recessive mental retardation-41. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:47475144-47484268
Strand Reverse strand
Band q13.32
Transcripts
ENST00000338134 ENSP00000337850
ENST00000595554 ENSP00000469446
ENST00000594139
ENST00000595484
ENST00000602193
ENST00000594208 ENSP00000470364
ENST00000600551
ENST00000598699
ENST00000600271 ENSP00000472291
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0006928 cellular component movement
GO:0007015 actin filament organization
GO:0007605 sensory perception of sound
Cellular Component
GO:0005634 nucleus
GO:0005815 microtubule organizing center
GO:0015629 actin cytoskeleton
GO:0030426 growth cone
GO:0032420 stereocilium
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006021
View Gene Order
ENSBTAG00000030769
Not yet available
Cross-References
SwissProt
TrEMBL M0R238
UniProt Splice Variant
Entrez Gene 11133
UniGene Hs.25441
RefSeq NM_007059
HUGO HGNC:6404
OMIM 615620
CCDS CCDS42583
HPRD 17241
IMGT
EMBL AC073548
GenPept
RNA Seq Atlas 11133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca