Homo sapiens Gene: REEP1
Summary
InnateDB Gene IDBG-59778.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REEP1
Gene Name receptor accessory protein 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000068615
Encoded Proteins
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
receptor accessory protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in this gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:86213993-86338083
Strand Reverse strand
Band p11.2
Transcripts
ENST00000165698 ENSP00000165698
ENST00000437769 ENSP00000401140
ENST00000453231 ENSP00000392197
ENST00000428491 ENSP00000400607
ENST00000490915
ENST00000473407
ENST00000489855 ENSP00000475269
ENST00000475475
ENST00000541910 ENSP00000442681
ENST00000538924 ENSP00000438346
ENST00000535845 ENSP00000437567
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
GO:0031849 olfactory receptor binding
Biological Process
GO:0008219 cell death
GO:0032386 regulation of intracellular transport
GO:0051205 protein insertion into membrane
GO:0071786 endoplasmic reticulum tubular network organization
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9H902
TrEMBL E7ESS5
UniProt Splice Variant
Entrez Gene 65055
UniGene Hs.368884 Hs.622683
RefSeq NM_001164732 NM_001164730 NM_001164731 NM_022912 XM_006712078
HUGO HGNC:25786
OMIM 609139
CCDS CCDS54373 CCDS1989 CCDS54372 CCDS54374
HPRD 07810
IMGT
EMBL AC009309 AC009408 AK023172 AK297201 AK297287 AK299334 AY562239 BC064846 CH471053 CR457301
GenPept AAH64846 AAT70684 AAX93132 BAB14444 BAH12523 BAH12538 BAH13005 CAG33582 EAW99457 EAW99458
RNA Seq Atlas 65055