Version 5.4
Homo sapiens Gene: MMD
Summary
InnateDB Gene IDBG-60062.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMD
Gene Name monocyte to macrophage differentiation-associated
Synonyms MMA; MMD1; PAQR11
Species Homo sapiens
Ensembl Gene ENSG00000108960
Encoded Proteins
IDBP-60064
monocyte to macrophage differentiation-associated
IDBP-760016
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:55392613-55421992
Strand Reverse strand
Band q22
Transcripts
ENST00000262065 ENSP00000262065
ENST00000571578 ENSP00000459202
ENST00000577038
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
Biological Process
GO:0019835 cytolysis
Cellular Component
GO:0005765 lysosomal membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031902 late endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003948
View Gene Order
ENSBTAG00000000205
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.463483
RefSeq NM_012329
HUGO
OMIM
CCDS CCDS11586
HPRD 06835
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca