Version 5.4
| Homo sapiens Gene: CST1 | |||||
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| Summary | |||||
| InnateDB Gene | IDBG-60283.5 | ||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||
| Gene Symbol | CST1 | ||||
| Gene Name | cystatin SN | ||||
| Synonyms | |||||
| Species | Homo sapiens | ||||
| Ensembl Gene | ENSG00000170373 | ||||
| Encoded Proteins |
cystatin SN
cystatin SN
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||
| Entrez Gene | |||||
| Summary |
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||
| Type | Protein coding | ||||
| Genomic Location | Chromosome 20:23747553-23751268 | ||||
| Strand | Reverse strand | ||||
| Band | p11.21 | ||||
| Transcripts |
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| Interactions | |||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||
| No orthologs found for this gene | |||||
| Pathways | |||||
| NETPATH | |||||
| REACTOME | |||||
| KEGG |
Salivary secretion pathway
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| INOH | |||||
| PID NCI | |||||
| Cross-References | |||||
| SwissProt | P01037 | ||||
| TrEMBL | |||||
| UniProt Splice Variant | |||||
| Entrez Gene | 1469 | ||||
| UniGene | |||||
| RefSeq | NM_001898 | ||||
| HUGO | HGNC:2473 | ||||
| OMIM | 123855 | ||||
| CCDS | CCDS13160 | ||||
| HPRD | 00460 | ||||
| IMGT | |||||
| EMBL | AL591074 BC021225 J03870 M19169 | ||||
| GenPept | AAA36115 AAA60299 AAH21225 CAC94783 | ||||
| RNA Seq Atlas | 1469 | ||||