Version 5.4
Homo sapiens Gene: KCNJ14
Summary
InnateDB Gene IDBG-60521.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ14
Gene Name potassium inwardly-rectifying channel, subfamily J, member 14
Synonyms IRK4; KIR2.4
Species Homo sapiens
Ensembl Gene ENSG00000182324
Encoded Proteins
IDBP-60523
potassium inwardly-rectifying channel, subfamily J, member 14
IDBP-246787
potassium inwardly-rectifying channel, subfamily J, member 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48455509-48466980
Strand Forward strand
Band q13.33
Transcripts
ENST00000342291 ENSP00000341479
ENST00000391884 ENSP00000375756
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
GO:0030425 dendrite
GO:0043025 neuronal cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058743
View Gene Order
ENSBTAG00000000082
Not yet available
Pathways
NETPATH
REACTOME
REACT_75870
Classical Kir channels pathway
REACT_13685
Neuronal System pathway
REACT_75918
Inwardly rectifying K+ channels pathway
REACT_75908
Potassium Channels pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9UNX9
TrEMBL
UniProt Splice Variant
Entrez Gene 3770
UniGene Hs.590945
RefSeq NM_013348
HUGO HGNC:6260
OMIM 603953
CCDS CCDS12721
HPRD 04901
IMGT
EMBL AF081466 AF181988 BC035918
GenPept AAD51376 AAF97619 AAH35918
RNA Seq Atlas 3770

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca