Mus musculus Gene: Cldn20
Summary
InnateDB Gene IDBG-605264.2
Last Modified 2013-04-25 [Report errors or provide feedback]
Gene Symbol Cldn20
Gene Name claudin 20
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000091530
Encoded Proteins
claudin 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is identified in retinal pigment epithelium (RPE) and analysis of the RPE transcriptome reveals that this gene expression appears late during development of chick embryo. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:3532554-3533213
Strand Forward strand
Band A1
Transcripts
ENSMUST00000168560 ENSMUSP00000126169
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Tight junction pathway
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Hepatitis C pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Tight junction interactions pathway
Cell-Cell communication pathway
Cell junction organization pathway
Cell-cell junction organization pathway
KEGG
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Tight junction pathway
Hepatitis C pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G5E8X0
UniProt Splice Variant
Entrez Gene 621628
UniGene Mm.469914
RefSeq NM_001101560
OMIM
CCDS CCDS49928
HPRD
IMGT
MGI ID MGI:3646757
MGI Symbol Cldn20
EMBL AC122350 CH466633
GenPept EDL01645
RNA Seq Atlas 621628