Version 5.4
| Mus musculus Gene: Serpinb10 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-606065.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Serpinb10 | ||||||
| Gene Name | serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10 | ||||||
| Synonyms | |||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000092572 | ||||||
| Encoded Proteins |
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000242550:
The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by a well-conserved tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-10 (PI10; SERPINB10) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).[supplied by OMIM, Jan 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 1:107529003-107549271 | ||||||
| Strand | Forward strand | ||||||
| Band | E2.1 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Amoebiasis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Amoebiasis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | G3UYR4 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 241197 | ||||||
| UniGene | |||||||
| RefSeq | NM_001160307 NM_198028 | ||||||
| OMIM | |||||||
| CCDS | CCDS48338 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:2138648 | ||||||
| MGI Symbol | Serpinb10 | ||||||
| EMBL | AC148982 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 241197 | ||||||