Version 5.4
Mus musculus Gene: Hspa1b
Summary
InnateDB Gene IDBG-606687.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hspa1b
Gene Name heat shock protein 1B
Synonyms hsp68; Hsp70; Hsp70-1; Hsp70.1
Species Mus musculus
Ensembl Gene ENSMUSG00000090877
Encoded Proteins
IDBP-627914
heat shock protein 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23135720
HSPA1B is released extracellularly upon measles virus infection, and induces Ifnb transcription in microglial cells.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:34956436-34959238
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000172753 ENSMUSP00000133815
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
Experimentally validated
Total 58 [view]
Protein-Protein 57 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006950 response to stress
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_198687
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
REACT_188957
Cellular responses to stress pathway
REACT_198693
AUF1 (hnRNP D0) destabilizes mRNA pathway
REACT_213550
HSF1-dependent transactivation pathway
REACT_224790
Cellular response to heat stress pathway
REACT_223784
Attenuation phase pathway
REACT_233572
Gene Expression pathway
REACT_222185
Regulation of HSF1-mediated heat shock response pathway
KEGG
mmu04612
Antigen processing and presentation pathway
mmu04010
MAPK signaling pathway pathway
mmu04144
Endocytosis pathway
mmu03040
Spliceosome pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
mmu05145
Toxoplasmosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.372314 Mm.469237
RefSeq NM_010478
OMIM
CCDS CCDS37592
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca