Version 5.4
Homo sapiens Gene: DBP
Summary
InnateDB Gene IDBG-60848.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DBP
Gene Name D site of albumin promoter (albumin D-box) binding protein
Synonyms DABP
Species Homo sapiens
Ensembl Gene ENSG00000105516
Encoded Proteins
IDBP-60850
D site of albumin promoter (albumin D-box) binding protein
IDBP-762740
IDBP-760939
IDBP-761564
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythym genes. [provided by RefSeq, Jan 2012]
The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48630030-48637438
Strand Reverse strand
Band q13.33
Transcripts
ENST00000222122 ENSP00000222122
ENST00000593500 ENSP00000471220
ENST00000599385 ENSP00000469426
ENST00000601104 ENSP00000469291
ENST00000594723
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001889 liver development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048511 rhythmic process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000059824
View Gene Order
ENSBTAG00000006754
Not yet available
Pathways
NETPATH
REACTOME
REACT_111118
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
REACT_24941
Circadian Clock pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL M0QXW3
UniProt Splice Variant
Entrez Gene 1628
UniGene Hs.414480
RefSeq NM_001352
HUGO HGNC:2697
OMIM 124097
CCDS CCDS12728
HPRD 00497
IMGT
EMBL AC008888 AC022154
GenPept
RNA Seq Atlas 1628

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca