Version 5.4
Homo sapiens Gene: TEX14
Summary
InnateDB Gene IDBG-61347.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TEX14
Gene Name testis expressed 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000121101
Encoded Proteins
IDBP-61349
testis expressed 14
IDBP-61351
testis expressed 14
IDBP-61353
testis expressed 14
IDBP-761620
IDBP-762727
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:58556678-58692055
Strand Reverse strand
Band q22
Transcripts
ENST00000349033 ENSP00000268910
ENST00000240361 ENSP00000240361
ENST00000389934 ENSP00000374584
ENST00000582740 ENSP00000463593
ENST00000584699
ENST00000581147 ENSP00000463243
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019901 protein kinase binding
Biological Process
GO:0006468 protein phosphorylation
GO:0007094 mitotic spindle assembly checkpoint
GO:0007140 male meiosis
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0032091 negative regulation of protein binding
GO:0032466 negative regulation of cytokinesis
GO:0043063 intercellular bridge organization
GO:0051306 mitotic sister chromatid separation
Cellular Component
GO:0000776 kinetochore
GO:0000777 condensed chromosome kinetochore
GO:0005623 cell
GO:0005737 cytoplasm
GO:0030496 midbody
GO:0045171 intercellular bridge
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000010342
View Gene Order
ENSBTAG00000010167
Not yet available
Cross-References
SwissProt Q8IWB6
TrEMBL J3QLK3
UniProt Splice Variant
Entrez Gene 56155
UniGene Hs.390221
RefSeq NM_001201457 NM_031272 NM_198393 XM_005257518 XM_005257519 XM_006721976 XM_006721977
HUGO HGNC:11737
OMIM 605792
CCDS CCDS32692 CCDS32693 CCDS56042
HPRD
IMGT
EMBL AC005666 AC011195 AF285601 AL834143 BC040526 BK000998
GenPept AAH40526 AAK31980 CAD38856 DAA01359
RNA Seq Atlas 56155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca