Version 5.4
Homo sapiens Gene: ZNF41
Summary
InnateDB Gene IDBG-61388.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF41
Gene Name zinc finger protein 41
Synonyms MRX89
Species Homo sapiens
Ensembl Gene ENSG00000147124
Encoded Proteins
IDBP-61390
zinc finger protein 41
IDBP-61392
zinc finger protein 41
IDBP-369342
zinc finger protein 41
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:47445879-47482946
Strand Reverse strand
Band p11.3
Transcripts
ENST00000377065 ENSP00000366265
ENST00000313116 ENSP00000315173
ENST00000432977 ENSP00000390385
ENST00000465311
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P51814
TrEMBL A0A024R1C4
UniProt Splice Variant
Entrez Gene 7592
UniGene Hs.496074
RefSeq XM_005272666 XM_005272668 XM_005272669 NM_007130 NM_153380 XM_005272665 XM_006724556 XM_006724557
HUGO HGNC:13107
OMIM 314995
CCDS CCDS14279
HPRD 02447
IMGT
EMBL AJ010017 AJ010018 AJ010019 AJ010020 AJ010021 AJ010022 AJ010023 AK290021 AK294858 AL590223 AL590283 BC015023 CH471164 M92443 X60155
GenPept AAA61312 AAH15023 BAF82710 BAG57962 CAB51740 CAB53035 CAB53036 CAB53037 CAB53038 CAB53039 CAB53040 CAB53041 CAI41591 CAI41627 EAW59303 EAW59304 EAW59308
RNA Seq Atlas 7592

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca