Version 5.4
Homo sapiens Gene: WDR66
Summary
InnateDB Gene IDBG-62068.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WDR66
Gene Name WD repeat domain 66
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000158023
Encoded Proteins
IDBP-62070
WD repeat domain 66
IDBP-235353
WD repeat domain 66
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:121917862-122003927
Strand Forward strand
Band q24.31
Transcripts
ENST00000288912 ENSP00000288912
ENST00000397454 ENSP00000380595
ENST00000428465
ENST00000540779
ENST00000546044
ENST00000543211
ENST00000535257
ENST00000545752
ENST00000545988
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000029442
View Gene Order
ENSBTAG00000004187
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.602740 Hs.678426 Hs.709837
RefSeq NM_001178003 NM_144668
HUGO
OMIM
CCDS CCDS41853 CCDS53840
HPRD 14570
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca