Version 5.4
Homo sapiens Gene: OTUD1
Summary
InnateDB Gene IDBG-62776.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OTUD1
Gene Name OTU domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165312
Encoded Proteins
IDBP-62778
OTU domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:23439458-23442390
Strand Forward strand
Band p12.2
Transcripts
ENST00000376495 ENSP00000365678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
Biological Process
GO:0006508 proteolysis
GO:0070536 protein K63-linked deubiquitination
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043415
View Gene Order
ENSBTAG00000047752
Not yet available
Cross-References
SwissProt Q5VV17
TrEMBL
UniProt Splice Variant
Entrez Gene 220213
UniGene Hs.499042 Hs.601151
RefSeq NM_001145373
HUGO HGNC:27346
OMIM 612022
CCDS CCDS44366
HPRD
IMGT
EMBL AL512603
GenPept CAH73715
RNA Seq Atlas 220213

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca