Version 5.4
Bos taurus Gene: BT.57732
Summary
InnateDB Gene IDBG-628385.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.57732
Gene Name myomesin-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009387
Encoded Proteins
IDBP-679766
myomesin (M-protein) 2, 165kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000036448:
The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:312538-376193
Strand Forward strand
Band
Transcripts
ENSBTAT00000012351 ENSBTAP00000012351
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006936 muscle contraction
Cellular Component
GO:0005739 mitochondrion
GO:0031430 M band
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000036448
View Gene Order
ENSMUSG00000031461
View Gene Order
Cross-References
SwissProt
TrEMBL E1BF23
UniProt Splice Variant
Entrez Gene 524077
UniGene Bt.57732 Bt.89432
RefSeq NM_001038140 XM_005225909 XM_005225910 XM_005225911 XM_005225912
HUGO HGNC:7614
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059735 DAAA02059736 DAAA02059737 DAAA02059738 DAAA02059739
GenPept
RNA Seq Atlas 524077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca