Bos taurus Gene: SUGT1
Summary
InnateDB Gene IDBG-628629.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SUGT1
Gene Name Suppressor of G2 allele of SKP1 homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002137
Encoded Proteins
Suppressor of G2 allele of SKP1 homolog
Suppressor of G2 allele of SKP1 homolog
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] Positively regulates NOD1 activation
[Homo sapiens] Bridges the HSP90 molecular chaperone system to the substrate-specific arm of SCF ubiquitin ligase complexes, suggesting a role in SCF assembly and regulation, and providing multiple complementary routes for ubiquitination of Hsp90 client proteins
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165416:
This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:11131393-11172149
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002771 ENSBTAP00000002771
ENSBTAT00000002770 ENSBTAP00000002770
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Inflammasomes pathway
The NLRP3 inflammasome pathway
Immune System pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
Innate Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
The NLRP3 inflammasome pathway
Inflammasomes pathway
Innate Immune System pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
Immune System pathway
Innate Immune System pathway
Immune System pathway
The NLRP3 inflammasome pathway
Inflammasomes pathway
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways pathway
KEGG
NOD-like receptor signaling pathway pathway
NOD-like receptor signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q2KIK0
TrEMBL
UniProt Splice Variant
Entrez Gene 515509
UniGene
RefSeq NM_001046203 XM_005213631
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC112610
GenPept AAI12611
RNA Seq Atlas 515509