Version 5.4
Bos taurus Gene: LASS3
Summary
InnateDB Gene IDBG-628637.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LASS3
Gene Name ceramide synthase 3
Synonyms LASS3
Species Bos taurus
Ensembl Gene ENSBTAG00000006987
Encoded Proteins
IDBP-680002
LAG1 longevity assurance homolog 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154227:
Gene Information
Type Protein coding
Genomic Location Chromosome 21:6262124-6420992
Strand Forward strand
Band
Transcripts
ENSBTAT00000052579 ENSBTAP00000052564
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0050291 sphingosine N-acyltransferase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0030148 sphingolipid biosynthetic process
GO:0030216 keratinocyte differentiation
GO:0046513 ceramide biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000154227
View Gene Order
ENSMUSG00000030510
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
REACT_198151
Sphingolipid de novo biosynthesis pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
mmu00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.74492
RefSeq NM_001099389 XM_005221766 XM_005221767 XM_005221768
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca