Version 5.4
Bos taurus Gene: ADAMTS6
Summary
InnateDB Gene IDBG-628776.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTS6
Gene Name A disintegrin and metalloproteinase with thrombospondin motifs 6 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016963
Encoded Proteins
IDBP-680165
ADAM metallopeptidase with thrombospondin type 1 motif, 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000049192:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:14008347-14285012
Strand Forward strand
Band
Transcripts
ENSBTAT00000061189 ENSBTAP00000053837
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000049192
View Gene Order
ENSMUSG00000046169
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22161
Post-translational protein modification pathway
REACT_200727
O-linked glycosylation pathway
REACT_17015
Metabolism of proteins pathway
REACT_200626
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BK03
UniProt Splice Variant
Entrez Gene 540722
UniGene Bt.24904
RefSeq NM_001193016 XM_005221461 XM_005221462 XM_005221463 XM_005221464 XM_005221465 XM_005221466 XM_005221467 XM_005221468 XM_005221469 XM_005221470 XM_005221471 XM_005221472 XM_005221473 XM_005221474 XM_005221475 XM_005221476 XM_005221477 XM_005221478 XM_005221480
HUGO HGNC:222
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050152 DAAA02050153 DAAA02050154 DAAA02050155 DAAA02050156 DAAA02050157 DAAA02050158 DAAA02050159 DAAA02050160 DAAA02050161 DAAA02050162
GenPept
RNA Seq Atlas 540722

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca