Version 5.4
| Bos taurus Gene: LSM1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-629170.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | LSM1 | ||||||||
| Gene Name | U6 snRNA-associated Sm-like protein LSm1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000001612 | ||||||||
| Encoded Proteins |
U6 snRNA-associated Sm-like protein LSm1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000175324:
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 27:33042449-33051041 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
mRNA decay by 5' to 3' exoribonuclease pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
mRNA decay by 5' to 3' exoribonuclease pathway
Deadenylation-dependent mRNA decay pathway
Gene Expression pathway
mRNA decay by 5' to 3' exoribonuclease pathway
Gene Expression pathway
Deadenylation-dependent mRNA decay pathway
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| KEGG |
RNA degradation pathway
RNA degradation pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q5E9Z8 | ||||||||
| TrEMBL | Q2YDJ3 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 535447 | ||||||||
| UniGene | Bt.2005 | ||||||||
| RefSeq | |||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC110194 BT020738 BT020771 BT020779 | ||||||||
| GenPept | AAI10195 AAX08755 AAX08788 AAX08796 | ||||||||
| RNA Seq Atlas | 535447 | ||||||||