Version 5.4
Bos taurus Gene: COL12A1
Summary
InnateDB Gene IDBG-629669.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol COL12A1
Gene Name collagen alpha-1(XII) chain precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020056
Encoded Proteins
IDBP-681304
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111799:
This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:14869511-14983763
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026725 ENSBTAP00000026725
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005615 extracellular space
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000111799
View Gene Order
ENSMUSG00000032332
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121139
Collagen biosynthesis and modifying enzymes pathway
REACT_150401
Collagen degradation pathway
REACT_118779
Extracellular matrix organization pathway
REACT_118572
Degradation of the extracellular matrix pathway
REACT_120729
Collagen formation pathway
REACT_199045
Collagen formation pathway
REACT_198984
Collagen biosynthesis and modifying enzymes pathway
REACT_206066
Extracellular matrix organization pathway
KEGG
hsa04974
Protein digestion and absorption pathway
mmu04974
Protein digestion and absorption pathway
INOH
INOH website
Integrin signaling pathway pathway
INOH website
Integrin signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1N401 Q9TRM6
UniProt Splice Variant
Entrez Gene 359712
UniGene Bt.107357 Bt.7380
RefSeq NM_001206497 XM_005210664 XM_005210665
HUGO HGNC:2188
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025271
GenPept
RNA Seq Atlas 359712

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca