InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ESCO2

Summary

InnateDB Gene

IDBG-629736.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ESCO2

Gene Name

N-acetyltransferase ESCO2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006551

Encoded Proteins

IDBP-681153

N-acetyltransferase ESCO2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171320:
This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:10859329-10885722

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000008606

ENSBTAP00000008606

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004468	lysine N-acetyltransferase activity

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0006275	regulation of DNA replication
GO:0006302	double-strand break repair
GO:0007059	chromosome segregation
GO:0034421	post-translational protein acetylation
GO:0071168	protein localization to chromatin

Cellular Component

GO:0000785	chromatin
GO:0001741	XY body
GO:0005634	nucleus
GO:0005794	Golgi apparatus
GO:0010369	chromocenter
GO:0031618	nuclear centromeric heterochromatin
GO:0035861	site of double-strand break