Bos taurus Gene: DGKB
Summary
InnateDB Gene IDBG-629766.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DGKB
Gene Name diacylglycerol kinase beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021905
Encoded Proteins
diacylglycerol kinase, beta 90kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136267:
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:22333433-23127587
Strand Reverse strand
Band
Transcripts
ENSBTAT00000061250 ENSBTAP00000053176
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003951 NAD+ kinase activity
GO:0004143 diacylglycerol kinase activity
GO:0005509 calcium ion binding
Biological Process
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008152 metabolic process
GO:0016310 phosphorylation
GO:0035556 intracellular signal transduction
Cellular Component
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Effects of PIP2 hydrolysis pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Hemostasis pathway
GPCR downstream signaling pathway
Hemostasis pathway
Signaling by GPCR pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Platelet activation, signaling and aggregation pathway
Effects of PIP2 hydrolysis pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
KEGG
Glycerophospholipid metabolism pathway
Phosphatidylinositol signaling system pathway
Glycerolipid metabolism pathway
Glycerophospholipid metabolism pathway
Phosphatidylinositol signaling system pathway
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B7U7
UniProt Splice Variant
Entrez Gene 537171
UniGene Bt.105799 Bt.48044
RefSeq NM_001192898 XM_005205199 XM_005205200 XM_005205201
HUGO HGNC:2850
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02009961 DAAA02009962 DAAA02009963 DAAA02009964 DAAA02009965 DAAA02009966 DAAA02009967 DAAA02009968 DAAA02009969 DAAA02009970 DAAA02009971
GenPept
RNA Seq Atlas 537171