Version 5.4
Bos taurus Gene: BT.66017
Summary
InnateDB Gene IDBG-629775.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.66017
Gene Name TATA box-binding protein-associated factor RNA polymerase I subunit C
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018772
Encoded Proteins
IDBP-681200
TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103168:
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:10472573-10482376
Strand Reverse strand
Band
Transcripts
ENSBTAT00000056158 ENSBTAP00000051454
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000103168
View Gene Order
ENSMUSG00000031832
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1074
RNA Polymerase I Transcription Termination pathway
REACT_2204
RNA Polymerase I Chain Elongation pathway
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_200827
SIRT1 negatively regulates rRNA Expression pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
REACT_245058
RNA Polymerase I Transcription pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_257165
RNA Polymerase I Transcription Termination pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_224328
SIRT1 negatively regulates rRNA Expression pathway
REACT_233572
Gene Expression pathway
REACT_207809
Negative epigenetic regulation of rRNA expression pathway
REACT_232235
RNA Polymerase I Promoter Escape pathway
REACT_240511
RNA Polymerase I Promoter Clearance pathway
REACT_259097
RNA Polymerase I Chain Elongation pathway
REACT_235780
RNA Polymerase I Transcription Initiation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MUD5
UniProt Splice Variant
Entrez Gene 509238
UniGene Bt.3952 Bt.66017
RefSeq NM_001077888
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046172
GenPept
RNA Seq Atlas 509238

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca