Bos taurus Gene: CA5A
Summary
InnateDB Gene IDBG-630301.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CA5A
Gene Name carbonic anhydrase 5A, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010151
Encoded Proteins
carbonic anhydrase VA, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174990:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:13389828-13412237
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013397 ENSBTAP00000013397
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004089 carbonate dehydratase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Reversible hydration of carbon dioxide pathway
Metabolism pathway
Metabolism pathway
Reversible hydration of carbon dioxide pathway
KEGG
Nitrogen metabolism pathway
Nitrogen metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BAD9
UniProt Splice Variant
Entrez Gene 515359
UniGene Bt.88214
RefSeq NM_001192409
HUGO HGNC:1377
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02046227
GenPept
RNA Seq Atlas 515359