InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ATP5J

Summary

InnateDB Gene

IDBG-630313.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ATP5J

Gene Name

ATP synthase-coupling factor 6, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000605

Encoded Proteins

IDBP-681759

ATP synthase-coupling factor 6, mitochondrial

IDBP-681761

ATP synthase-coupling factor 6, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000154723:
Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the F6 subunit of the Fo complex, required for F1 and Fo interactions. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. A pseudogene exists on chromosome Yp11.[provided by RefSeq, Jun 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:10069680-10076995

Strand

Forward strand

Band

Transcripts

ENSBTAT00000032427	ENSBTAP00000032359
ENSBTAT00000066011	ENSBTAP00000054675

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0015078	hydrogen ion transmembrane transporter activity
GO:0016887	ATPase activity

Biological Process

GO:0006200	ATP catabolic process
GO:0006810	transport
GO:0006811	ion transport
GO:0015986	ATP synthesis coupled proton transport
GO:0015992	proton transport
GO:0021762	substantia nigra development

Cellular Component

GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005753	mitochondrial proton-transporting ATP synthase complex
GO:0016020	membrane
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)