Bos taurus Gene: BT.24212
Summary
InnateDB Gene IDBG-630416.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.24212
Gene Name R-spondin-3 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008121
Encoded Proteins
R-spondin-3 precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146374:
This gene encodes a member of the thrombospondin type 1 repeat supergene family. In addition, the protein contains a furin-like cysteine-rich region. Furin-like repeat domains have been found in a variety of eukaryotic proteins involved in the mechanism of signal transduction by receptor tyrosine kinases. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:24365333-24508267
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010680 ENSBTAP00000010680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005109 frizzled binding
GO:0008201 heparin binding
Biological Process
GO:0060070 canonical Wnt signaling pathway
GO:0060670 branching involved in labyrinthine layer morphogenesis
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
Wnt pathway
REACTOME
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Signal Transduction pathway
regulation of FZD by ubiquitination pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
Disease pathway
Signaling by Wnt pathway
Signaling by WNT in cancer pathway
regulation of FZD by ubiquitination pathway
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
TCF dependent signaling in response to WNT pathway
Signal Transduction pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL G5E599
UniProt Splice Variant
Entrez Gene 534650
UniGene Bt.24212
RefSeq NM_001076034
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025519 DAAA02025520 DAAA02025521 DAAA02025522 DAAA02025523 DAAA02025524 DAAA02025525 DAAA02025526 DAAA02025527 DAAA02025528 DAAA02025529
GenPept
RNA Seq Atlas 534650