Version 5.4
Bos taurus Gene: BT.55194
Summary
InnateDB Gene IDBG-630478.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.55194
Gene Name alanine--glyoxylate aminotransferase 2, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007690
Encoded Proteins
IDBP-681943
alanine--glyoxylate aminotransferase 2, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113492:
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:39156953-39199656
Strand Forward strand
Band
Transcripts
ENSBTAT00000010113 ENSBTAP00000010113
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008453 alanine-glyoxylate transaminase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0009436 glyoxylate catabolic process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
GO:0019481 L-alanine catabolic process, by transamination
GO:0045429 positive regulation of nitric oxide biosynthetic process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000113492
View Gene Order
ENSMUSG00000089678
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16925
Glyoxylate metabolism pathway
REACT_1023
Pyrimidine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_957
Pyrimidine metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_236186
Pyrimidine metabolism pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
REACT_261828
Glyoxylate metabolism pathway
REACT_241108
Pyrimidine catabolism pathway
REACT_245662
Metabolism of nucleotides pathway
KEGG
hsa00260
Glycine, serine and threonine metabolism pathway
hsa00250
Alanine, aspartate and glutamate metabolism pathway
mmu00260
Glycine, serine and threonine metabolism pathway
mmu00250
Alanine, aspartate and glutamate metabolism pathway
INOH
INOH website
Glycolysis Gluconeogenesis pathway
INOH website
Alanine Aspartate Asparagine metabolism pathway
INOH website
Glycine Serine metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL F1MLG7
UniProt Splice Variant
Entrez Gene 521553
UniGene Bt.55194
RefSeq NM_001075821
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02050661
GenPept
RNA Seq Atlas 521553

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca