Version 5.4
Bos taurus Gene: NR1D2
Summary
InnateDB Gene IDBG-630509.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NR1D2
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000018024
Encoded Proteins
IDBP-681997
nuclear receptor subfamily 1, group D, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. [provided by RefSeq, Feb 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 27:41866520-41883521
Strand Reverse strand
Band
Transcripts
ENSBTAT00000023994 ENSBTAP00000023994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001046 core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0003708 retinoic acid receptor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0019216 regulation of lipid metabolic process
GO:0042752 regulation of circadian rhythm
GO:0043401 steroid hormone mediated signaling pathway
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048384 retinoic acid receptor signaling pathway
GO:0050727 regulation of inflammatory response
GO:0055088 lipid homeostasis
GO:2000505 regulation of energy homeostasis
GO:2001014 regulation of skeletal muscle cell differentiation
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000174738
View Gene Order
ENSMUSG00000021775
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_15525
Nuclear Receptor transcription pathway pathway
REACT_12627
Generic Transcription Pathway pathway
REACT_71
Gene Expression pathway
REACT_234105
Nuclear Receptor transcription pathway pathway
REACT_233572
Gene Expression pathway
REACT_206529
Generic Transcription Pathway pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MWI2
UniProt Splice Variant
Entrez Gene 532076
UniGene Bt.39270
RefSeq XM_002698756 XM_610586
HUGO HGNC:7963
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02061153 DAAA02061154
GenPept
RNA Seq Atlas 532076

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca