InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: KCNJ10

Summary

InnateDB Gene

IDBG-630657.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KCNJ10

Gene Name

ATP-sensitive inward rectifier potassium channel 10

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000002414

Encoded Proteins

IDBP-682126

potassium inwardly-rectifying channel, subfamily J, member 10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000177807:
This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:9720672-9755813

Strand

Forward strand

Band

Transcripts

ENSBTAT00000003132

ENSBTAP00000003132

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005242	inward rectifier potassium channel activity
GO:0005244	voltage-gated ion channel activity
GO:0005267	potassium channel activity
GO:0005515	protein binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006813	potassium ion transport
GO:0007601	visual perception
GO:0007628	adult walking behavior
GO:0014003	oligodendrocyte development
GO:0022010	central nervous system myelination
GO:0034765	regulation of ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0051935	L-glutamate uptake involved in synaptic transmission
GO:0055075	potassium ion homeostasis
GO:0060075	regulation of resting membrane potential
GO:0071805	potassium ion transmembrane transport