Bos taurus Gene: BT.87340
Summary
InnateDB Gene IDBG-630661.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.87340
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005653
Encoded Proteins
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000005471:
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:33120503-33193999
Strand Forward strand
Band
Transcripts
ENSBTAT00000007432 ENSBTAP00000007432
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0008152 metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0046581 intercellular canaliculus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
KEGG
ABC transporters pathway
Bile secretion pathway
ABC transporters pathway
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BLT5
UniProt Splice Variant
Entrez Gene 100336913
UniGene Bt.110213 Bt.59013 Bt.87340
RefSeq XM_002686717 XM_003582070 XM_005205299 XM_005205300 XM_005205302
HUGO HGNC:45
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02010247 DAAA02010248 DAAA02010249 DAAA02010250 DAAA02010251
GenPept
RNA Seq Atlas 100336913