Version 5.4
Bos taurus Gene: MTIF3
Summary
InnateDB Gene IDBG-630760.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTIF3
Gene Name Translation initiation factor IF-3, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020530
Encoded Proteins
IDBP-682242
Translation initiation factor IF-3, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122033:
This gene encodes a translation initiation factor that is involved in mitochondrial protein synthesis. Polymorphism in this gene is associated with the onset of Parkinson's disease. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:32720219-32723627
Strand Forward strand
Band
Transcripts
ENSBTAT00000027352 ENSBTAP00000027352
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0008135 translation factor activity, nucleic acid binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0001732 formation of translation initiation complex
GO:0006412 translation
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122033
View Gene Order
ENSMUSG00000016510
View Gene Order
Pathways
NETPATH
REACTOME
REACT_270797
Mitochondrial translation initiation pathway
REACT_270450
Mitochondrial translation pathway
REACT_219259
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_200751
Organelle biogenesis and maintenance pathway
REACT_267673
Mitochondrial translation pathway
REACT_267680
Mitochondrial translation initiation pathway
REACT_268789
Mitochondrial translation pathway
REACT_224594
Organelle biogenesis and maintenance pathway
REACT_271096
Mitochondrial translation initiation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q32KZ1
TrEMBL
UniProt Splice Variant
Entrez Gene 509987
UniGene Bt.30788
RefSeq NM_001038066 XM_005213770 XM_005213771 XM_005213772 XM_005213773
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC109845
GenPept AAI09846
RNA Seq Atlas 509987

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca