Bos taurus Gene: UNC5CL
Summary
InnateDB Gene IDBG-630764.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UNC5CL
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002919
Encoded Proteins
unc-5 homolog C (C. elegans)-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
[Homo sapiens] UNC5CL is a factor in epithelial inflammation where it activates the pro-inflammatory IRAK signalling cascade in a MYD88-independent manner.
[Mus musculus] Unc5cl is a factor in epithelial inflammation where it activates the pro-inflammatory IRAK signalling cascade in a Myd88-independent manner.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124602:
Gene Information
Type Protein coding
Genomic Location Chromosome 23:14959072-14965828
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003791 ENSBTAP00000003791
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007165 signal transduction
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046330 positive regulation of JNK cascade
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
TNFalpha pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq XM_002697231 XM_005192913 XM_005192914 XM_005192915 XM_005192916 XM_005192917 XM_005192918 XM_005192919 XM_005223515 XM_005223516 XM_005223517 XM_005223518 XM_005223519 XM_005223520 XM_866859
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas