Bos taurus Gene: BT.105073
Summary
InnateDB Gene IDBG-630771.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105073
Gene Name transcription factor IIIA
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012600
Encoded Proteins
transcription factor IIIA
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:32723124-32733098
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016732 ENSBTAP00000016732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
RNA Polymerase III Abortive And Retractive Initiation pathway
RNA Polymerase III Transcription Initiation From Type 1 Promoter pathway
RNA Polymerase III Transcription Initiation pathway
RNA Polymerase III Transcription pathway
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
Gene Expression pathway
KEGG
INOH
PID NCI
IL4-mediated signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.105073
RefSeq NM_001113572 XM_005213759
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas