Version 5.4
Bos taurus Gene: STAMBP
Summary
InnateDB Gene IDBG-631439.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAMBP
Gene Name STAM-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009600
Encoded Proteins
IDBP-682978
STAM-binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000124356:
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:10771666-10795813
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012633 ENSBTAP00000012633
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
Biological Process
GO:0000281 mitotic cytokinesis
GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016579 protein deubiquitination
GO:0043524 negative regulation of neuron apoptotic process
GO:0046580 negative regulation of Ras protein signal transduction
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0032154 cleavage furrow
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000124356
View Gene Order
ENSMUSG00000006906
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04144
Endocytosis pathway
mmu04144
Endocytosis pathway
INOH
PID NCI
erbb1_internalization_pathway
Internalization of ErbB1
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.9164
RefSeq NM_001075971 XM_005212477 XM_005212478 XM_005212479
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca