Version 5.4
Bos taurus Gene: MAPK8
Summary
InnateDB Gene IDBG-631635.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAPK8
Gene Name mitogen-activated protein kinase 8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000007876
Encoded Proteins
IDBP-683185
mitogen-activated protein kinase 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 28:43160797-43196195
Strand Forward strand
Band
Transcripts
ENSBTAT00000010361 ENSBTAP00000010361
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004705 JUN kinase activity
GO:0004707 MAP kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0035033 histone deacetylase regulator activity
GO:0042826 histone deacetylase binding
Biological Process
GO:0001503 ossification
GO:0006468 protein phosphorylation
GO:0007254 JNK cascade
GO:0007258 JUN phosphorylation
GO:0009103 lipopolysaccharide biosynthetic process
GO:0009411 response to UV
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0016310 phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0031063 regulation of histone deacetylation
GO:0032091 negative regulation of protein binding
GO:0032880 regulation of protein localization
GO:0043066 negative regulation of apoptotic process
GO:0046686 response to cadmium ion
GO:0070301 cellular response to hydrogen peroxide
GO:0071222 cellular response to lipopolysaccharide
GO:0071260 cellular response to mechanical stimulus
GO:0071732 cellular response to nitric oxide
GO:0090045 positive regulation of deacetylase activity
GO:0097300 programmed necrotic cell death
GO:2000017 positive regulation of determination of dorsal identity
GO:2001235 positive regulation of apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.14050
RefSeq NM_001192974 XM_005226583 XM_005226584 XM_005226585 XM_005226586 XM_005226588 XM_005226589
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca