Version 5.4
Bos taurus Gene: ALCAM
Summary
InnateDB Gene IDBG-631637.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ALCAM
Gene Name CD166 antigen precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000088
Encoded Proteins
IDBP-683194
CD166 antigen precursor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170017:
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:50332272-50558841
Strand Forward strand
Band
Transcripts
ENSBTAT00000000097 ENSBTAP00000000097
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007411 axon guidance
GO:0008045 motor neuron axon guidance
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030424 axon
GO:0043025 neuronal cell body
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000170017
View Gene Order
ENSMUSG00000022636
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22205
L1CAM interactions pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_261444
Axon guidance pathway
REACT_219680
L1CAM interactions pathway
REACT_188576
Developmental Biology pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MHN8
UniProt Splice Variant
Entrez Gene 281614
UniGene Bt.107510
RefSeq NM_174238 XM_005201256
HUGO HGNC:400
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001191
GenPept
RNA Seq Atlas 281614

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca