Version 5.4
Bos taurus Gene: DACH1
Summary
InnateDB Gene IDBG-631661.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DACH1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000043985
Encoded Proteins
IDBP-683210
dachshund homolog 1 (Drosophila)
IDBP-683211
dachshund homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:46417100-46430892
Strand Reverse strand
Band
Transcripts
ENSBTAT00000065251 ENSBTAP00000056290
ENSBTAT00000061013 ENSBTAP00000053865
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001075 RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001967 suckling behavior
GO:0006355 regulation of transcription, DNA-templated
GO:0007585 respiratory gaseous exchange
GO:0008283 cell proliferation
GO:0046545 development of primary female sexual characteristics
GO:0048147 negative regulation of fibroblast proliferation
GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly
GO:0060244 negative regulation of cell proliferation involved in contact inhibition
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
null
View Gene Order
ENSMUSG00000055639
View Gene Order
Cross-References
SwissProt
TrEMBL G3N318
UniProt Splice Variant
Entrez Gene 537184
UniGene
RefSeq XM_002691884 XM_617340
HUGO HGNC:2663
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02033456
GenPept
RNA Seq Atlas 537184
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca