Bos taurus Gene: RIT1
Summary
InnateDB Gene IDBG-631822.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIT1
Gene Name GTP-binding protein Rit1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000000105
Encoded Proteins
GTP-binding protein Rit1
GTP-binding protein Rit1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143622:
This gene encodes a member of a subfamily of Ras-related GTPases. The encoded protein is involved in regulating p38 MAPK-dependent signaling cascades related to cellular stress. This protein also cooperates with nerve growth factor to promote neuronal development and regeneration. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:14908141-14917339
Strand Forward strand
Band
Transcripts
ENSBTAT00000000114 ENSBTAP00000000114
ENSBTAT00000064030 ENSBTAP00000054335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006184 GTP catabolic process
GO:0006886 intracellular protein transport
GO:0006913 nucleocytoplasmic transport
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0007265 Ras protein signal transduction
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Signalling to p38 via RIT and RIN pathway
Signalling by NGF pathway
Signal Transduction pathway
Signalling to ERKs pathway
NGF signalling via TRKA from the plasma membrane pathway
Signalling to ERKs pathway
Signalling by NGF pathway
NGF signalling via TRKA from the plasma membrane pathway
Signal Transduction pathway
Signalling to p38 via RIT and RIN pathway
KEGG
INOH
PID NCI
Trk receptor signaling mediated by the MAPK pathway
Neurotrophic factor-mediated Trk receptor signaling
Cross-References
SwissProt
TrEMBL G3MXR6
UniProt Splice Variant
Entrez Gene 533646
UniGene Bt.66435
RefSeq NM_001098078
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007149
GenPept
RNA Seq Atlas 533646