Version 5.4
Bos taurus Gene: CLIC5
Summary
InnateDB Gene IDBG-632263.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CLIC5
Gene Name chloride intracellular channel protein 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010244
Encoded Proteins
IDBP-683863
chloride intracellular channel protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112782:
This gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin-based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation, myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:19167358-19333272
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013537 ENSBTAP00000013537
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005247 voltage-gated chloride channel activity
GO:0005515 protein binding
Biological Process
GO:0002021 response to dietary excess
GO:0002024 diet induced thermogenesis
GO:0006821 chloride transport
GO:0007605 sensory perception of sound
GO:0008104 protein localization
GO:0044070 regulation of anion transport
GO:0050885 neuromuscular process controlling balance
GO:0060088 auditory receptor cell stereocilium organization
Cellular Component
GO:0015629 actin cytoskeleton
GO:0016020 membrane
GO:0032420 stereocilium
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000112782
View Gene Order
ENSMUSG00000023959
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.194
RefSeq NM_174276
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca