InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC35A1

Summary

InnateDB Gene

IDBG-632597.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC35A1

Gene Name

CMP-sialic acid transporter

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014057

Encoded Proteins

IDBP-684225

CMP-sialic acid transporter

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164414:
The protein encoded by this gene is found in the membrane of the Golgi apparatus, where it transports nucleotide sugars into the Golgi. One such nucleotide sugar is CMP-sialic acid, which is imported into the Golgi by the encoded protein and subsequently glycosylated. Defects in this gene are a cause of congenital disorder of glycosylation type 2F (CDG2F). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:63302749-63334395

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000018680

ENSBTAP00000018680

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005338	nucleotide-sugar transmembrane transporter activity
GO:0005351	sugar:proton symporter activity

Biological Process

GO:0006810	transport
GO:0008643	carbohydrate transport
GO:0015780	nucleotide-sugar transport
GO:0015992	proton transport
GO:0055085	transmembrane transport
GO:1901679	nucleotide transmembrane transport