Version 5.4
Homo sapiens Gene: RARRES1
Summary
InnateDB Gene IDBG-63283.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RARRES1
Gene Name retinoic acid receptor responder (tazarotene induced) 1
Synonyms LXNL; TIG1
Species Homo sapiens
Ensembl Gene ENSG00000118849
Encoded Proteins
IDBP-63285
retinoic acid receptor responder (tazarotene induced) 1
IDBP-477428
retinoic acid receptor responder (tazarotene induced) 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:158696892-158732696
Strand Reverse strand
Band q25.32
Transcripts
ENST00000237696 ENSP00000237696
ENST00000462663
ENST00000479756 ENSP00000418556
ENST00000471444
ENST00000498640
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0008285 negative regulation of cell proliferation
Cellular Component
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049404
View Gene Order
ENSBTAG00000014713
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.131269 Hs.708627
RefSeq NM_002888 NM_206963 XM_005247686
HUGO
OMIM
CCDS CCDS3184 CCDS54665
HPRD 05477
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca