Bos taurus Gene: UBE4B | |||||||||||
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Summary | |||||||||||
InnateDB Gene | IDBG-633294.2 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | UBE4B | ||||||||||
Gene Name | ubiquitin conjugation factor E4 B | ||||||||||
Synonyms | |||||||||||
Species | Bos taurus | ||||||||||
Ensembl Gene | ENSBTAG00000010401 | ||||||||||
Encoded Proteins |
ubiquitin conjugation factor E4 B
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Protein Structure | |||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
Entrez Gene | |||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130939:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||
Type | Protein coding | ||||||||||
Genomic Location | Chromosome 16:44263938-44385466 | ||||||||||
Strand | Reverse strand | ||||||||||
Band | |||||||||||
Transcripts |
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Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||
NETPATH | |||||||||||
REACTOME | |||||||||||
KEGG |
Ubiquitin mediated proteolysis pathway
Protein processing in endoplasmic reticulum pathway
Ubiquitin mediated proteolysis pathway
Protein processing in endoplasmic reticulum pathway
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INOH | |||||||||||
PID NCI |
p73 transcription factor network
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Cross-References | |||||||||||
SwissProt | |||||||||||
TrEMBL | A6QNS2 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 520833 | ||||||||||
UniGene | Bt.17976 | ||||||||||
RefSeq | NM_001102504 | ||||||||||
HUGO | |||||||||||
OMIM | |||||||||||
CCDS | |||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | BC148970 DAAA02042992 | ||||||||||
GenPept | AAI48971 | ||||||||||
RNA Seq Atlas | 520833 | ||||||||||