Version 5.4
Bos taurus Gene: DTX3L
Summary
InnateDB Gene IDBG-633305.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DTX3L
Gene Name E3 ubiquitin-protein ligase DTX3L
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009933
Encoded Proteins
IDBP-685002
deltex 3-like (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163840:
DTX3L functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).[supplied by OMIM, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:67588920-67597019
Strand Forward strand
Band
Transcripts
ENSBTAT00000013108 ENSBTAP00000013108
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0042393 histone binding
GO:0046872 metal ion binding
Biological Process
GO:0006302 double-strand break repair
GO:0006974 cellular response to DNA damage stimulus
GO:0010390 histone monoubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163840
View Gene Order
ENSMUSG00000049502
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
hsa04330
Notch signaling pathway pathway
mmu04330
Notch signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BH71
UniProt Splice Variant
Entrez Gene 515051
UniGene Bt.106168 Bt.28523
RefSeq NM_001192396
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02001605
GenPept
RNA Seq Atlas 515051

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca