InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: AMPD3

Summary

InnateDB Gene

IDBG-633321.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AMPD3

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015821

Encoded Proteins

IDBP-685058

adenosine monophosphate deaminase 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000133805:
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:42759305-42796464

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000021018

ENSBTAP00000021018

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003876	AMP deaminase activity
GO:0019239	deaminase activity

Biological Process

GO:0006188	IMP biosynthetic process
GO:0032264	IMP salvage
GO:0046031	ADP metabolic process
GO:0046033	AMP metabolic process
GO:0046034	ATP metabolic process
GO:0097009	energy homeostasis