Bos taurus Gene: BT.105015
Summary
InnateDB Gene IDBG-633419.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.105015
Gene Name Non-lysosomal glucosylceramidase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011431
Encoded Proteins
Non-lysosomal glucosylceramidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070610:
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:60316734-60327815
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015194 ENSBTAP00000015194
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004348 glucosylceramidase activity
GO:0008422 beta-glucosidase activity
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006680 glucosylceramide catabolic process
GO:0021954 central nervous system neuron development
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
KEGG
Sphingolipid metabolism pathway
Other glycan degradation pathway
Sphingolipid metabolism pathway
Other glycan degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MND2
UniProt Splice Variant
Entrez Gene 100139170
UniGene Bt.105015
RefSeq XM_001790070 XM_002689680 XM_005199224 XM_005210144
HUGO HGNC:18986
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02023131
GenPept
RNA Seq Atlas 100139170