Version 5.4
Bos taurus Gene: SNX4
Summary
InnateDB Gene IDBG-633631.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX4
Gene Name Sorting nexin-4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011383
Encoded Proteins
IDBP-685359
Sorting nexin-4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114520:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:70504978-70557887
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015120 ENSBTAP00000015120
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006810 transport
GO:0006886 intracellular protein transport
GO:0015031 protein transport
GO:0032456 endocytic recycling
Cellular Component
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005868 cytoplasmic dynein complex
GO:0016020 membrane
GO:0031901 early endosome membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000114520
View Gene Order
ENSMUSG00000022808
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_7
TGF_beta_Receptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt A1A4L0
TrEMBL
UniProt Splice Variant
Entrez Gene 519597
UniGene Bt.68600 Bt.7574
RefSeq NM_001080281
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126650
GenPept AAI26651
RNA Seq Atlas 519597

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca