Version 5.4
Bos taurus Gene: RPL27A
Summary
InnateDB Gene IDBG-633633.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPL27A
Gene Name 60S ribosomal protein L27a
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005349
Encoded Proteins
IDBP-685356
60S ribosomal protein L27a
IDBP-685361
60S ribosomal protein L27a
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166441:
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:44469327-44472127
Strand Reverse strand
Band
Transcripts
ENSBTAT00000025126 ENSBTAP00000042947
ENSBTAT00000007036 ENSBTAP00000007036
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 46 interaction(s) predicted by orthology.
Predicted by orthology
Total 46 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005622 intracellular
GO:0005840 ribosome
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000166441
View Gene Order
ENSMUSG00000057036
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_79
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_75768
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_75822
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_2085
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
REACT_1797
Formation of a pool of free 40S subunits pathway
REACT_1986
Eukaryotic Translation Termination pathway
REACT_1404
Peptide chain elongation pathway
REACT_1477
Eukaryotic Translation Elongation pathway
REACT_115902
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_9491
Viral mRNA Translation pathway
REACT_2159
Eukaryotic Translation Initiation pathway
REACT_6167
Influenza Infection pathway
REACT_75886
Nonsense-Mediated Decay (NMD) pathway
REACT_6152
Influenza Viral RNA Transcription and Replication pathway
REACT_1014
Translation pathway
REACT_17015
Metabolism of proteins pathway
REACT_2099
Cap-dependent Translation Initiation pathway
REACT_6145
Influenza Life Cycle pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
REACT_253640
Peptide chain elongation pathway
REACT_254308
Translation pathway
REACT_231519
Eukaryotic Translation Termination pathway
REACT_198522
Nonsense-Mediated Decay (NMD) pathway
REACT_247926
Metabolism of proteins pathway
REACT_198528
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_198524
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
REACT_229570
Cap-dependent Translation Initiation pathway
REACT_262064
Eukaryotic Translation Initiation pathway
REACT_196445
SRP-dependent cotranslational protein targeting to membrane pathway
REACT_232254
Eukaryotic Translation Elongation pathway
REACT_249044
Formation of a pool of free 40S subunits pathway
REACT_233572
Gene Expression pathway
REACT_259469
L13a-mediated translational silencing of Ceruloplasmin expression pathway
REACT_262078
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
KEGG
hsa03010
Ribosome pathway
mmu03010
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.23343 Bt.77124
RefSeq NM_001024471
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca