Bos taurus Gene: MRPL28
Summary
InnateDB Gene IDBG-633684.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MRPL28
Gene Name 39S ribosomal protein L28, mitochondrial
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016581
Encoded Proteins
39S ribosomal protein L28, mitochondrial
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000086504:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75%% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 25:361740-364295
Strand Reverse strand
Band
Transcripts
ENSBTAT00000022057 ENSBTAP00000022057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0005840 ribosome
GO:0030529 ribonucleoprotein complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Mitochondrial translation initiation pathway
Mitochondrial translation elongation pathway
Mitochondrial translation pathway
Mitochondrial translation termination pathway
Organelle biogenesis and maintenance pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Organelle biogenesis and maintenance pathway
Mitochondrial translation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
Mitochondrial translation elongation pathway
Mitochondrial translation pathway
Organelle biogenesis and maintenance pathway
Mitochondrial translation elongation pathway
Mitochondrial translation initiation pathway
Mitochondrial translation termination pathway
KEGG
Ribosome pathway
Ribosome pathway
INOH
PID NCI
Cross-References
SwissProt Q2HJJ1
TrEMBL M5FMT5
UniProt Splice Variant
Entrez Gene 508216
UniGene
RefSeq NM_001045996 XM_005224409
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC105311 GJ062847
GenPept AAI05312 DAA15558
RNA Seq Atlas 508216