Bos taurus Gene: PTPRR | |||||||||||||||
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Summary | |||||||||||||||
InnateDB Gene | IDBG-633690.3 | ||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
Gene Symbol | PTPRR | ||||||||||||||
Gene Name | receptor-type tyrosine-protein phosphatase R isoform 2 precursor | ||||||||||||||
Synonyms | PCPTP1 | ||||||||||||||
Species | Bos taurus | ||||||||||||||
Ensembl Gene | ENSBTAG00000015311 | ||||||||||||||
Encoded Proteins |
protein tyrosine phosphatase, receptor type, R isoform 2
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Protein Structure | |||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
Entrez Gene | |||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000153233:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011] |
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Gene Information | |||||||||||||||
Type | Protein coding | ||||||||||||||
Genomic Location | Chromosome 5:42837597-43112731 | ||||||||||||||
Strand | Forward strand | ||||||||||||||
Band | |||||||||||||||
Transcripts |
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Interactions | |||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||
NETPATH |
EGFR1 pathway
FSH pathway
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REACTOME | |||||||||||||||
KEGG |
MAPK signaling pathway pathway
MAPK signaling pathway pathway
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INOH | |||||||||||||||
PID NCI | |||||||||||||||
Cross-References | |||||||||||||||
SwissProt | |||||||||||||||
TrEMBL | A5PKF8 | ||||||||||||||
UniProt Splice Variant | |||||||||||||||
Entrez Gene | 536337 | ||||||||||||||
UniGene | Bt.1069 Bt.109341 | ||||||||||||||
RefSeq | NM_001113261 | ||||||||||||||
HUGO | |||||||||||||||
OMIM | |||||||||||||||
CCDS | |||||||||||||||
HPRD | |||||||||||||||
IMGT | |||||||||||||||
EMBL | BC142472 DAAA02013191 DAAA02013192 DAAA02013193 DAAA02013194 DAAA02013195 DAAA02013196 DAAA02013197 DAAA02013198 | ||||||||||||||
GenPept | AAI42473 | ||||||||||||||
RNA Seq Atlas | 536337 | ||||||||||||||