Bos taurus Gene: LMO1
Summary
InnateDB Gene IDBG-633701.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMO1
Gene Name Rhombotin-1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016320
Encoded Proteins
Rhombotin-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166407:
This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:44880076-44917824
Strand Forward strand
Band
Transcripts
ENSBTAT00000045558 ENSBTAP00000042937
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q0P5B3
TrEMBL
UniProt Splice Variant
Entrez Gene 527152
UniGene Bt.63080
RefSeq NM_001075895 XM_005215975
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120273
GenPept AAI20274
RNA Seq Atlas 527152