Version 5.4
Bos taurus Gene: BT.104044
Summary
InnateDB Gene IDBG-633722.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.104044
Gene Name TFIIA-alpha and beta-like factor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000023999
Encoded Proteins
IDBP-685445
STON1-GTF2A1L protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000242441:
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:30763319-30811999
Strand Forward strand
Band
Transcripts
ENSBTAT00000005456 ENSBTAP00000005456
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006367 transcription initiation from RNA polymerase II promoter
Cellular Component
GO:0005672 transcription factor TFIIA complex
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000024154
View Gene Order
ENSG00000242441
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
mmu03022
Basal transcription factors pathway
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1MSE9
UniProt Splice Variant
Entrez Gene 505979
UniGene Bt.104044
RefSeq NM_001080229 XM_005212574
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02030760
GenPept
RNA Seq Atlas 505979

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca